A reappraisal of lymph node dissection in colorectal cancer during primary surgical resection

• DOI: 10.1186/s12957-020-01863-2
• Publication Date: 2020-05-17T14:02:17Z
• Authors: Yen-Jen Chen; Shin-Ting Yeh; Ping-Sheng Kao; Liang-Hung Ou; Chen-Sung Lin
• Keywords: Surgical oncology

Abstract Purpose Controversy exists regarding the extent to which lymph node dissection (LND) should be performed for operable colorectal cancers (CRCs) during primary surgical resection. We reappraised role of LND in CRCs. Methods Seventy-three CRC patients (mean age, 65.3 years; 43 males) undergoing resection at Taipei Hospital, Ministry Health and Welfare, Taiwan, within a 3-year period were retrospectively analyzed. Their pathological T/N/M statuses cancer stages defined according American Joint Committee on Cancer (AJCC) 8th edition staging system. The numbers total dissected nodes (TDLNs), positive (PDLNs), negative (NDLNs) each patient recorded detail (TDLNs = PDLNs + NDLNs). Possible prognostic variables evaluated. Results An advanced N status (N1/N2 vs. N0; HR, 5.749/17.677 1.000; p 0.056/0.009) M1 (M1 M0; 7.517 0.010) independent poor prognosis. For all 73 ( 0.030), as well T2 0.061), those with > 15 TDLNs tended have more than ≤ TDLNs. 42 N(+) 0.007), N2 0.011), 21 Conclusion resection, number influences accuracy nodal staging. A minimum is necessary identified patients, sufficient severity distinguished patients.