Epidemiological trends of sepsis in the twenty-first century (2000–2013): an analysis of incidence, mortality, and associated costs in Spain

• DOI: 10.1186/s12963-018-0160-x
• Publication Date: 2018-02-12T08:08:47Z
• Authors: Alejandro Álvaro-...; María A. Jiménez-...; Dariela Micheloud; Ainhoa Sánchez-Lopez; María Heredia-Rod...; Eduardo Tamayo; Salvador Resino
• Keywords: Case fatality rate

Sepsis has represented a substantial health care and economic burden worldwide during the previous several decades. Our aim was to analyze epidemiological trends of hospital admissions, deaths, resource expenditures, associated costs related sepsis twenty-first century in Spain. We performed retrospective study all sepsis-related hospitalizations Spanish public hospitals from 2000 2013. Data were obtained records Minimum Basic Set. The outcome variables sepsis, death, length stay (LOHS), sepsis-associated costs. period divided into three calendar periods (2000–2004, 2005–2009, 2010–2013). Overall, 2,646,445 patients with included, 485,685 whom had died (18.4%). incidence (events per 1000 population) increased 3.30 (2000–2004) 4.28 (2005–2009) 4.45 (2010–2013) (p < 0.001). mortality rates (deaths 10,000 6.34 7.88 7.89 case fatality rate (CFR) or proportion who decreased 19.1% 18.4% 17.9% LOHS (days) 15.9 15.7 14.5 Total patient 2011, then by impact crisis. caused an increasing terms admission, system century, but seemed stabilize 2010–2013. Moreover, there significant decrease 2010–2013 decline after 2011.