Flow diverter effect of LVIS stent on cerebral aneurysm hemodynamics: a comparison with Enterprise stents and the Pipeline device

• DOI: 10.1186/s12967-016-0959-9
• Publication Date: 2016-07-01T21:06:35Z
• Authors: Chao Wang; Zhongbin Tian; Jian Liu; Linkai Jing; Nikhil Paliwal; Shengzhang Wang; Ying Zhang; Jianping Xiang; Adnan H. Siddiqui; Hui Meng; Xinjian Yang
• Keywords: Flow diverter; Cerebrovascular Circulation

The aim of this study was to quantify the effect new Low-profile Visualized Intraluminal Support (LVIS®D) device and difference fluid diverting compared with Pipeline Enterprise stent using computational dynamics (CFD).In research, we simulated three aneurysms constructed from 3D digital subtraction angiography (DSA). Enterprise, LVIS were virtually conformed fit into vessel lumen placed across aneurysm orifice. Computational analysis performed compare hemodynamic differences such as WSS, Velocity Pressure among these stents.Control referred unstented model, percentage changes all Control. A single caused more wall shear stress reduction than double stents (39.96 vs. 30.51 %) velocity (23.13 18.64 %). Significant in (63.88 (46.05 observed double-LVIS stents. showed less WSS (51.08 (37.87 stent. double-Pipeline resulted most (72.37 (54.26 Moreover, pressure increased minuscule extent after stenting, model.This is first analyzing flow modifications associated We found that has certain effects on cerebral aneurysms: a reductions double-Enterprise but device. Nevertheless, better