Validation of in vivo 2D displacements from spiral cine DENSE at 3T

• DOI: 10.1186/s12968-015-0119-z
• Publication Date: 2015-01-29T13:33:10Z
• Authors: Gregory J Wehner; Jonathan D Suever; Christopher M Hag...; Linyuan Jing; David K Powell; Sean M Hamlet; Jonathan D Grabau; Walter Dimitri Mo...; Xiaodong Zhong; Frederick H Epstein; Brandon K Fornwalt
• Keywords: Root mean square

Displacement Encoding with Stimulated Echoes (DENSE) encodes displacement into the phase of magnetic resonance signal. Due to stimulated echo, signal is inherently low and fades through cardiac cycle. To compensate, a spiral acquisition has been used at 1.5T. This sequence not validated 3T, where increased would be valuable, but field inhomogeneities may result in measurement errors. We hypothesized that cine DENSE valid 3T tested this hypothesis by measuring errors both 1.5T vivo. Two-dimensional tagged imaging left ventricle were performed on ten healthy subjects six Intersection points identified images near end-systole. Displacements from project those back their origins. The deviation perfect grid was as measure accuracy quantified root-mean-squared error. compared between Wilcoxon rank sum test. Inter-observer variability strains torsion agreement harmonic (HARP) assessed Bland-Altman analyses. noise ratio (SNR) each different (1.2 ± 0.3 mm 1.2 0.4 mm, respectively). Both values lower than pixel spacing 2.8 mm. There no substantial differences inter-observer or HARP Relative 1.5T, SNR greater factor 1.4 0.3. displacements can applied equivalent accuracy. DENSE-derived peak also comparable strengths. Future studies take advantage additional 3T.