African guidelines for diagnosis and management of polyarticular juvenile idiopathic arthritis: PAFLAR initiative

• DOI: 10.1186/s12969-025-01076-5
• Publication Date: 2025-03-15T10:41:54Z
• Authors: Mohammed Hassan A...; Angela Nyangore M...; Hanna Lishan Kassa; Wassila Messadi; Yassmine Taha; Yaninga Halwani F...; Madeleine Ngandeu; Yasser El Miedany; Michael Hofer; Wafa Hamdi; Temesgen Teferi Libe; Ali Sobh; Waleed Hassan; Yasmine Makhlouf; Ayodele Faleye; Soad Hashed; Samah Ismail Nasef; Chafia Dahou Makh...; Elisa Palalane; Hanene Lassoued F...; Ahmed Seri; Doaa Mosad Mosa; Ourida Gacem; Francis Fredrick ...; Samy Slimani; Christiaan Scott; Djohra Hadef
• Keywords: Delphi Method

Abstract Background Juvenile idiopathic arthritis (JIA) is the most common rheumatologic disease of childhood. The Existing guidelines for polyarticular JIA are typically based on data from non-African populations and may not fully address unique challenges faced in African settings. We aimed to produce updated diagnosis treatment children adolescents with juvenile (poly-JIA). Methods This study was conducted aim reaching a consensus among experts poly-JIA using Delphi technique. first scientific committee identified total 15 key clinical questions according PICO (Patient/Population, Intervention, Comparison, Outcome) approach. A systematic review evidence-based literature this work. core steering group researchers clinicians expertise pediatric rheumatology. process used reach consensus. Results An online questionnaire sent expert panel that participated survey (100% response rate). recommendation points were identified, divided into two parts: five recommendations ten management. percentage those who agreed (fourth fifth place) ranged 80 100%. All statements had been upon wording (i.e., 75% respondents or strongly agreed). Conclusions successfully developed JIA, taking consideration specific nature limited resources low income, also same time incorporating newly released treat target