Surgical choice for patients with stage I non-small-cell lung cancer ≤2 cm: an analysis from surveillance, epidemiology, and end results database

• DOI: 10.1186/s13019-021-01568-x
• Publication Date: 2021-07-07T16:30:10Z
• Authors: Liang Wu; Weigang Zhao; Tangbing Chen; Yi Yang
• Keywords: Wedge resection; Lymphadenectomy; Univariate analysis; T-stage; Cardiothoracic surgery

Abstract Background No consensus was reached on the surgical procedure for patients with stage I non-small-cell lung cancer (NSCLC) ≤ 2 cm. The aim of this study is to investigate appropriate NSCLC ≤2 Methods Patients cm received wedge resection, segmentectomy, lobectomy between January 2004 and December 2015 were identified using Surveillance, Epidemiology, End Results (SEER) database. Data stratified by age, gender, race, side, location, grade, histology, extent lymphadenectomy. Overall survival (OS) cancer-specific (LCSS) compared among lobectomy. Univariate analysis multivariable Cox regression performed identify prognostic factors OS LCSS. A total 16,511 included in study, whom 2945 classified as ≤1 Lobectomy had better LCSS when resection Only favored segmentectomy NSCLC>1 Multivariable showed that similar Lymph node dissection (LND) associated Conclusions Segmentectomy comparable LND can provide more accurate pathological stage, may affect survival, should be recommended above patients.