Delay in diagnosis of influenza A (H1N1)pdm09 virus infection in critically ill patients and impact on clinical outcome
Adult
Male
Delayed Diagnosis
Critical Illness
610
Critical Care and Intensive Care Medicine
Influenzavirus
Statistics, Nonparametric
03 medical and health sciences
Influenza A Virus, H1N1 Subtype
0302 clinical medicine
Diagnòstic
Risk Factors
616
Diagnosis
Influenza, Human
Odds Ratio
Influenza viruses
Humans
Hospital Mortality
Prospective Studies
Mortality
Critically ill
Outcome
Aged
Chi-Square Distribution
Research
Length of Stay
Middle Aged
Influenza A (H1N1)pdm09 virus infection
Early diagnosis
Late diagnosis
3. Good health
Intensive Care Units
Logistic Models
Spain
ICU
Female
DOI:
10.1186/s13054-016-1512-1
Publication Date:
2016-10-17T16:02:52Z
AUTHORS (9)
ABSTRACT
Patients infected with influenza A (H1N1)pdm09 virus requiring admission to the ICU remain an important source of mortality during season. The objective study was assess impact a delay in diagnosis community-acquired infection on clinical outcome critically ill patients admitted ICU.A prospective multicenter observational cohort based data from GETGAG/SEMICYUC registry (2009-2015) collected by 148 Spanish ICUs. All which had been established within first week hospitalization were included. classified into two groups according time at made: early (within 2 days hospital admission) and late (between 3rd 7th day admission). Factors associated assessed logistic regression analysis.In 2059 diagnosed 7 hospitalization, 1314 (63.8 %) remaining 745 (36.2 %). Independent variables related were: age (odds ratio (OR) = 1.02, 95 % confidence interval (CI) 1.01-1.03, P < 0.001); seasonal period (2009-2012) (OR 2.08, CI 1.64-2.63, stay before 1.26, 1.17-1.35, mechanical ventilation 1.58, 1.17-2.13, 0.002); continuous venovenous hemofiltration 1.54, 1.08-2.18, 0.016). intra-ICU significantly higher among as compared (26.9 vs 17.1 %, 0.001). Diagnostic one independent risk factor for 1.36, 1.03-1.81, 0.001).Late is admission, greater possibilities respiratory renal failure, rate. Delay flu variable death.
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