MICRA: an automatic pipeline for fast characterization of microbial genomes from high-throughput sequencing data

• DOI: 10.1186/s13059-017-1367-z
• Publication Date: 2017-12-19T08:21:23Z
• Authors: Ségolène Caboche; Gaël Even; Alexandre Loywick; Christophe Audebert; David Hot
• Keywords: Identification

The increase in available sequence data has advanced the field of microbiology; however, making sense these without bioinformatics skills is still problematic. We describe MICRA, an automatic pipeline, as a web interface, for microbial identification and characterization through reads analysis. MICRA uses iterative mapping against reference genomes to identify genes variations. Additional modules allow prediction antibiotic susceptibility resistance comparing results several samples. fast, producing few false-positive annotations variant calls compared current methods, it tool great interest fully exploiting sequencing data.