Treatment of rheumatoid arthritis and its outcomes in an aging society: a single-center cohort study in Japan from 2011 to 2020

• DOI: 10.1186/s13075-022-02883-x
• Publication Date: 2022-08-09T10:02:52Z
• Authors: Wataru Fukuda; Masatoshi Kadoya; Atsushi Omoto; Takuya Yanagida; Yu Isoda; Atsuhiko Sunaga; Hiroaki Kusuoka; Kentaro Ueno; Satoshi Morita; Masataka Kohno; Yutaka Kawahito
• Keywords: Depression; Outpatient clinic

We conducted a single-center cohort study of rheumatoid arthritis (RA) patients from 2011 to 2020 understand their real world treatment and outcomes, especially changes in physical function quality life (QOL) elderly patients, including those aged ≥ 80 years.For RA attending our outpatient clinic, we annually recorded tender swollen joint counts, laboratory findings, therapeutic drugs, scores the Japanese Health Assessment Questionnaire EuroQoL-5 Dimensions questionnaire. examined outcomes over time, by age group, enrolled 10-year period, 2020.One thousand eight hundred thirty were data once year, total 9299 patient records evaluated. The average increased 3.7 years during period; rapidly. Intensive pharmacological was more frequent younger patients. Disease activity, function, QOL showed improvement all groups period. Physical greater with aging, compared disease activity. This may be due effects accumulated damage, disability depression.Intensive contributes not only control activity but also QOL, even Relieving age-related impairment depression improve very