Antimicrobial resistance patterns and genetic elements associated with the antibiotic resistance of Helicobacter pylori strains from Shanghai

• DOI: 10.1186/s13099-022-00488-y
• Publication Date: 2022-03-30T09:04:52Z
• Authors: Yixin Liu; Su Wang; Feng Yang; Wenjing Chi; Li Ding; Tao Liu; Feng Zhu; Danian Ji; Jun Zhou; Yi Fang; Jinghao Zhang; Ping Xiang; Yanmei Zhang; Hu Zhao
• Keywords: 23S ribosomal RNA; Medical microbiology

Shanghai, in east China, has one of the world's highest burdens Helicobacter pylori infection. While multidrug regimens can effectively eradicate H. pylori, increasing prevalence antibiotic resistance (AR) been recognized by WHO as 'high priority' for urgent need new therapies. Moreover, genetic characteristics AR Shanghai is under-reported. The purpose this study was to determine prevalence, re-substantiate resistance-conferring mutations, and investigate novel elements associated with AR.