Septic shock complicated by disseminated herpes simplex virus-1 infection: a case report

• DOI: 10.1186/s13256-021-02985-1
• Publication Date: 2021-08-07T23:04:09Z
• Authors: Amélie Boquet; Guillaume Boulay; Etienne Hautin; Nicolas Mottard
• Keywords: Surgical oncology; HSL and HSV

Herpes virus remains dormant in human cells and could reactivate under immunosuppressed conditions, such as prolonged critical illnesses. The phenomenon of viral replication during intensive care is well known, even patients without a history immunosuppression, but it usually does not have clinical impact. Systemic reactivation leads to DNA blood. It unclear whether this marker morbimortality or true pathogenic process. Therefore, what medical treatment most appropriate for simple replication. In organ damage suspected be induced by herpes virus, there no consensus on the duration. Here, we report rarely described case multiorgan failure implicating simplex discuss its treatment.A 53-year-old Caucasian woman was admitted unit septic shock. She presented pneumonia due Klebsiella pneumoniae. Two weeks after admission, she showed with acute respiratory distress syndrome circulation failure. had digestive cutaneous lesions typical 1. Blood polymerase chain reaction strongly virus-1 positive. No other bacteria, fungi, viruses were found. evolution rapidly favorable initiation antiviral treatment. Treatment stopped 3 well-conducted therapy. Curative-dose interrupted despite continuous positive blood results. context, prophylactic continued.We an exceptional presentation virus-1. diagnosis made based visceral absence responsible microorganisms. Intense key diagnostic element. There regarding duration, decisions should reaction.