Longitudinal field studies reveal early infection and persistence of influenza A virus in piglets despite the presence of maternally derived antibodies

• DOI: 10.1186/s13567-019-0655-x
• Publication Date: 2019-05-22T04:55:30Z
• Authors: Pia Ryt-Hansen; Inge Larsen; Charlotte Sonne K...; Jesper Schak Krog; Silke Wacheck; Lars Erik Larsen
• Keywords: Persistence (discontinuity); Viral Shedding; Blood sampling

A longitudinal study was performed in three Danish farrow to grower (30 kilos) herds over a 4-month period investigate the dynamics and clinical impacts of influenza virus (IAV) infections. In each herd, four batches consisting sows with five ear-tagged piglets were included. Nasal swabs and/or blood sampled from prior farrowing at weeks 1, 3, 5 end nursery period. Clinical examinations sampling time. The tested for IAV antibodies nasal samples, respectively. results revealed enzootically infected herds, where majority pigs during first after birth. Infected only 3 days age detected unit, also shedding virus. all low moderate numbers (ranging 3.6 20.7%) found be positive two consecutive times. Furthermore, signs respiratory disease associated detection. findings this documented that can persist as young despite presence maternally derived antibodies.