Pazopanib: a novel treatment option for aggressive fibromatosis

• DOI: 10.1186/s13569-016-0061-3
• Publication Date: 2016-11-14T11:44:04Z
• Authors: Gulcan Bulut; Anil Ozluk; Atike Pınar Erdogan; Ruchan Uslu; Nevra Elmas; Burcak Karaca
• Keywords: Pazopanib; Aggressive Fibromatosis; Surgical oncology

Aggressive fibromatosis (AF), also known as desmoid tumor, is an uncommon soft tissue neoplasm. AF does not metastasize, but it locally invasive and its propensity for recurrence after conservative resection well documented. No effective cytotoxic treatment has been reported, hence there a need novel strategies.We present the case of successfully treated with oral tyrosine kinase inhibitor, pazopanib, mild side effects. As far we know, this first complete response to pazopanib.Pazopanib might be option AF.