Admission of tetanus patients to the ICU: a retrospective multicentre study

• DOI: 10.1186/s13613-017-0333-y
• Publication Date: 2017-11-07T12:41:07Z
• Authors: Rafael Mahieu; Thomas Reydel; Adel Maamar; Jean-Marc Tadié; Angeline Jamet; Arnaud W. Thille; Nicolas Chudeau; Julien Huntzinger; Steven Grangé; Gaetan Beduneau; Anne Courte; Stephane Ehrmann; Jérémie Lemarié; Sébastien Gibot; Michael Darmon; Christophe Guitton; Julia Champey; Carole Schwebel; Jean Dellamonica; Thibaut Wipf; Ferhat Meziani; Damien Du Cheyron; Achille Kouatchet; Nicolas Lerolle
• Keywords: Interquartile range; SAPS II

Background: An extended course of tetanus (up to 6 weeks) requiring ICU admission and protracted mechanical ventilation (MV) may have a significant impact on short-and long-term survival.The subject is noteworthy deserves be discussed. Methods:Twenty-two ICUs in France performed screenings patients admitted between January 2000 December 2014.Retrospective data were collected from hospital databases through the registers town hall patients.Results: Seventy included 15 different ICUs.Sixty-three suffered severe or very according Ablett classification.The median age was 80 years [interquartile range 73-84], 86% women.Ninety per cent (n = 63) required MV for 36 days , 66% administration neuromuscular-blocking agent 23 [14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29].A nosocomial infection occurred 43 (61%).ICU 1-year mortality rates 14% 10) 16% 11), respectively.Forty-five deaths during first week.Advanced age, higher SAPS II, any infection, use vasopressors significantly associated with lower number alive without ventilator support by day 90.Age only factor that differed deceased survivors at 1 year (83 [81-85] vs. 79 [73-84] years, respectively; p 0.03).Sixty-one no impairment their functional status. Conclusion:In high-income country, mainly occurs healthy elderly women.Despite prolonged length stay, we observed low rate good