A remarkably diverse and well-organized virus community in a filter-feeding oyster

• DOI: 10.1186/s40168-022-01431-8
• Publication Date: 2023-01-07T10:05:53Z
• Authors: Jing-Zhe Jiang; Yi-Fei Fang; Hong-Ying Wei; Peng Zhu; Min Liu; Wen-Guang Yuan; Li-Ling Yang; Ying-Xiang Guo; Tao Jin; Mang Shi; Tuo Yao; Jie Lu; Ling-Tong Ye; Shao-Kun Shi; Meng Wang; Ming Duan; Dian-Chang Zhang
• Keywords: Human virome; Virus classification; Ostreidae; Marine bacteriophage

Abstract Background Viruses play critical roles in the marine environment because of their interactions with an extremely broad range potential hosts. Many studies viruses seawater have been published, but that inhabit animals largely neglected. Oysters are keystone species coastal ecosystems, yet as filter-feeding bivalves very large roosting numbers and co-habitation, it is not clear what role they virus transmission microbiome regulation. Results Here, we report a Dataset Oyster Virome (DOV) contains 728,784 nonredundant viral operational taxonomic unit contigs (≥ 800 bp) 3473 high-quality genomes, enabling first comprehensive overview both DNA RNA communities oyster Crassostrea hongkongensis . We discovered tremendous diversity among novel this using multiple approaches, including reads recruitment, units, genomes. Our results show these different from oceans or other habitats. In particular, high circoviruses found oysters indicates may be hotspots for circoviruses. Notably, were enriched random well-organized can respond to changes health state host external at compositional functional levels. Conclusions study, generated “knowledge landscape” virome, which has increased number known oyster-related by tens thousands. suggest provide unique habitat seawater, highlight importance exploration well essential still invisible regulating ecosystems.