Underlying mechanisms in the relationship between stress and alcohol consumption in regular and risky drinkers (MESA): methods and design of a randomized laboratory study
Motivation
AUD
Alcohol Drinking
Ethanol
Ad-libitum taste-test
BF1-990
3. Good health
TSST
Study Protocol
Alcoholism
03 medical and health sciences
0302 clinical medicine
Impulsive Behavior
Psychology
Humans
Acute stress
Risky alcohol consumption
DOI:
10.1186/s40359-022-00942-1
Publication Date:
2022-10-15T10:02:44Z
AUTHORS (5)
ABSTRACT
Abstract Background Excessive alcohol consumption and use disorders (AUD) are among the leading preventable causes of premature morbidity mortality considered a major public health concern. In order to reduce individual societal burden excessive use, it is crucial identify high-risk individuals at earlier stages provide effective interventions prevent further progression. Stressful experiences important risk factors for AUDs. However, underlying biological psychological mechanisms still poorly understood. Methods The project “Underlying in relationship between stress regular risky drinkers (MESA)” randomized controlled study that started December 2018 conducted laboratory setting, which aims moderators mediators acute drinkers. Regular randomly assigned induction or control condition. Several processes may mediate (emotional distress, endocrine autonomic reactivity, impulsivity, inhibitory control, motivational sensitization) moderate (trait childhood maltreatment, basal HPA-axis activity) relation investigated. As primary dependent variable, motivation consume following psychosocial measured. Discussion results this could help valuable targets future research on tailored stress-related consumption.
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