Surrogate markers of activity of AG-013736, a multi-target tyrosine kinase receptor inhibitor, in metastatic renal cell cancer (RCC)

• DOI: 10.1200/jco.2005.23.16_suppl.3003
• Publication Date: 2017-02-23T13:55:09Z
• Authors: O. Rixe; J.-B. Meric; J. Bloch; A. Gentile; R. Mouawad; V. Adam; D. Buthiau; D. Khayat
• Keywords: 03 medical and health sciences; 0302 clinical medicine; 3. Good health

3003 Background: Significant activity of AG-013736, an oral small molecule with potent inhibitory effects against the VEGF receptors 1 (VEGFR-1) and 2 (VEGFR-2) and PDGF receptor, is reported in a ...