The prevalence of metabolic risk factors in black men with prostate cancer undergoing consideration for androgen-deprivation therapy.

Dyslipidemia Osteopenia
DOI: 10.1200/jco.2011.29.15_suppl.e15082 Publication Date: 2017-02-23T18:58:03Z
ABSTRACT
e15082 Background: Androgen deprivation therapy (ADT) for prostate cancer (PCa) is associated with endocrine complications such as osteoporosis, weight gain, diabetes and dyslipidemia. However, in previous studies, the patient population has been predominantly white. The aim of this study was to examine relevant baseline characteristics, above-mentioned complications, a black presenting consideration ADT. information gained will help us further risk stratify regards possible Methods: A chart-based retrospective review conducted on all patients diagnosed PCa one provider an urban hospital between September 2007 July 2010 who were being considered Baseline data collected body mass index (BMI), Vitamin-D status, bone mineral density (BMD), lipid profile status. Overweight obesity classified BMI≥25 BMI≥30, respectively, sufficiency ≥30 ng/ml, osteopenia T scores -1 -2.5 osteoporosis ≤ -2.5. Results: total 180 had sufficient which 71.1%, (n=128 patients, mean age 68.0 years; range 45-93) black. Their origin from 16 countries 44.9 % African Americans 55.1% immigrants. At baseline, average BMI 28.1±5.9 SD (range 15.4-58.5; n=104) 42.3% overweight additional 31.7% obese. Mean levels 21.1±9.7 4.0-48.0; n=93) 80.7% insufficient. Osteopenia present 46.8% 6.4%, respectively. Dyslipidemia 40.6% 28.1% diabetes. Conclusions: large proportion men ADT are either or obese at baseline. prevalence insufficiency, low BMD, dyslipidemia also remarkably high. These should be helpful physicians considering population.
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