Racial disparities in aging-related comorbidity among breast cancer survivors.

• DOI: 10.1200/jco.2023.41.16_suppl.10555
• Publication Date: 2023-06-04T16:29:56Z
• Authors: Kirsten Nguyen; Cong Wang; Jill De Vis; Mason Alford; Marjan Rafat; Anuradha Bapsi Ch...; Xiao-Ou Shu
• Keywords: Depression

10555 Background: Black breast cancer (BC) patients have a higher mortality rate than their white counterparts, potentially due to age acceleration caused by and its treatments. However, epidemiological evidence is limited. Methods: Our study includes 1885 BC 1224 free women (controls) recruited at Vanderbilt University Medical Center from 2004 2021. Patient demographics aging-related outcomes were extracted the tumor registry or electronic health records. Aging-related included 28 comorbidities Charlson Comorbidity Index (CCI) baseline (biopsy) follow-up (latest clinical visit). The associations of status with CCI specific evaluated linear logistic regression models, respectively. race among cases. All analyses adjusted for age, information. Results: median time 10 years. had mean (1.32 vs 0.59, p<0.01) (beta=1.04, 95% CI=0.94-1.14) controls. Results individual showed that survivors risk developing cardiovascular disease, liver hypertension, hyperlipidemia, gastroesophageal reflux disease (GERD), depression. Among patients, diagnosed younger (52.0 55.8, p<0.01), but Whites. more likely develop peptic ulcer diabetes, second malignancy, GERD White survivors, even after adjustment comorbidities. [Table: see text]