Assessing inpatient outcomes for patients with small cell lung cancer presenting with superior vena cava thrombosis.

• DOI: 10.1200/jco.2023.41.16_suppl.8589
• Publication Date: 2023-06-04T16:12:44Z
• Authors: Jay Vakil; Ekrem Turk; Ayobami Gbenga Ol...; Vaishali Deenaday...; Rafaella Litvin; Khaldun Obeidat; Muhammad Bilal Ib...; Kunnal Batra
• Keywords: 03 medical and health sciences; 0302 clinical medicine; 3. Good health

8589 Background: Superior Vena Cava Syndrome (SVCS) is a condition characterized by obstruction of the SVC that can commonly be caused thrombus formation in SVC. Small cell lung cancer (SCLC) frequently results When severe enough, SVCS present as life-threatening oncological emergency. In this study we aim to explore baseline characteristics thrombosis (SVCT) patients with SCLC, prevalence US hospitalizations, and disparities regards race socioeconomic status. Methods: National Inpatient Sample was utilized obtain pertinent data. Total hospitalizations coexistent comorbidities SCLC were extracted from 2016 2019 database. Adult secondary diagnosis determined using ICD-10 codes. We studied racial differences well length stay (LOS), total hospital charges (THC), all-cause mortality outcomes without thrombosis. Statistical analysis performed on STATA, logistic regression analyses chi-square tests. Results: A 480,750 hospitalized for SCLC. 720 these had (0.15% patients). The mean age those thrombi significantly lower compared (64 vs. 69, p < 0.001). SVCT cohort statistically higher proportion black than other cohort. Charlson index (5.8 5, Average income between two groups similar. Medicaid private insurance utilization more common admissions SVCT. Patients presenting an increased LOS (10 6 days, 0.001) cost cohorts ($117,320 $80,806, 0.005). All-cause 7.7% presence odds inpatient (18.0%). Non-White races associated admissions. addition, also greater having concomitant pulmonary embolism during hospitalization. Conclusions: found race, type, impacted likelihood developing superior vena cava Though incidence rare, indicates poor prognostic factor Further studies evaluate factors are warranted. development subsequent syndrome potentially condition; addressing potential reversible risk could improve large subgroup related