Analysis of hospitalizations of patients with Kaposi sarcoma: A national population-based study.

• DOI: 10.1200/jco.2023.41.16_suppl.e18821
• Publication Date: 2023-06-04T16:03:39Z
• Authors: Philip Onyekaoso ...; Ayobami Gbenga Ol...; Ted Akhiwu; Ehizogie Edigin; Muhammad Bilal Ib...; Anthonia Ijeli; Osaigbokan Aihie; Dan Ran Castillo; Muhammad Nauman Riaz
• Keywords: Diagnosis code

e18821 Background: Kaposi sarcoma (KS) is a type of soft tissue due to infection with human herpes virus 8 (HHV-8) and can be associated acquired immunodeficiency syndrome [AIDS]. Recent national population data are scarce on reasons for hospitalizations, epidemiology, hospitalization outcomes patients KS in the United States (U.S). Methods: Data were abstracted from National Inpatient Sample (NIS) Database. This database largest collection inpatient admission U.S. It 20-percent stratified sample all discharges community hospitals, excluding rehabilitation long-term acute care hospitals. The numbers databases weighted optimize estimates. Hospitalizations obtained by searching hospitalizations that contained ICD-10 code “C46” as principal or secondary diagnosis. diagnosis main reason admission, while any other than principal, (or diagnosis) was recorded descending order frequency based organ system category specific total number discharges, baseline demographic characteristics, hospital length stay (LOS), charges recorded. STATA 16 used analysis. Since NIS contains de-identified data, Institutional Review Board (IRB) review waived. Results: There 32 million included 2020 database. Of those, 2,785 aged ≥18 years, who had either ICD 10 KS. Patients mainly males (91%), black (40%), mean age 48 mortality 9.3%, LOS 9 days, charge 132,476 U.S dollars. 5 most common categories infections (52.4%), cardiovascular (6.5%), respiratory (6.1%), neoplasm hematologic (5.6%), skin (5.6%). diagnoses Human [HIV] disease (29.1%), sepsis (12.7%), left leg cellulitis (2.7%), pneumonia (2.2%), Acute kidney injury (1.8%). Conclusions: mostly middle-aged men, high mortality, long LOS, significant charges. Infections HIV hospitalizations. Management underlying measures prevention, early detection, prompt treatment outpatient setting important preventing these patients.