Impact of COVID-19 pandemic on diagnosis, staging, and outcomes of patients with early-onset colorectal cancer.

• DOI: 10.1200/jco.2023.41.4_suppl.15
• Publication Date: 2023-01-24T21:05:07Z
• Authors: Daniel Martinez-P...; David Viñal; Jose Ángel García...; Antonio Rueda-Lara; Iciar Ruiz-Gutierrez; Diego Jiménez-Bou; Jesus Peña-Lopez; Gema Martin-Montalvo; Maria Alameda-Gui...; Laura Gutiérrez-S...; Antonio Barbachano; Javier Rodriguez-...; Pilar Bustamante-...; Maria Jesús Larriba; Asuncion Fernande...; Aurora Burgos; Maria Isabel Prie...; Laura Guerra Past...; Jose Manuel Gonza...; Nuria Rodriguez S...
• Keywords: Lymphovascular invasion; Pandemic

15 Background: Although we seem to be recovering from COVID-19, are now facing the long-term consequence of pandemic on vulnerable subgroup patients such as with early-onset colorectal cancer (EOCRC). We aim study how COVID-19 affected diagnosis and clinic-pathological characteristics, treatment outcomes EOCRC. Methods: This is an observational retrospective including EOCRC diagnosed between September 2016 August 2021 at Hospital Universitario La Paz, Madrid, Spain. Two cohorts were stablished: before after March 14, 2020, day first lockdown in Results: A total 1409 CRC included. Of those, 5,2% (n=75). Fifty-five (73%) 20 (27%) pre, post pandemic. The rate per month was 1,8 1,1 pre postpandemic group, respectively. Fifty percent group metastatic disease, while only 29% had stage IV prepandemic (P = 0,09). High tumor budding, surgical margins affected, lymphovascular, perineural invasion also pathological features more observed subgroup, although results not statistically significant. differences both groups depicted. After a median follow-up 23 months (33 14 respectively), 11 have died (15%). Median overall survival (OS) reached either group. At 12 months, 94% 89% alive Conclusions: has influenced staging Long-term needed assess this population. role primary care early referral these is, than ever, crucial. [Table: see text]