Corticosteroids for Immune-Related Adverse Events and Checkpoint Inhibitor Efficacy: Analysis of Six Clinical Trials

• DOI: 10.1200/jco.24.00191
• Publication Date: 2024-08-07T20:01:07Z
• Authors: Rik J. Verheijden; Jolien S. de Groot; Babs O. Fabriek; Miki N. Hew; Anne M. May; Karijn P.M. Suijk...
• Keywords: Immunosuppression; Prednisolone; Post-hoc analysis

Retrospective studies suggest that immunosuppressive treatment of immune-related adverse events (irAEs) impairs survival in patients with melanoma who received immune checkpoint inhibitors. Here, we study this association across tumor types using data from six international phase II/III registrational trials.