Left Ventricular Myocardial Impairment in Subclinical Hypothyroidism Assessed by a New Ultrasound Tool: Pulsed Tissue Doppler

• DOI: 10.1210/jc.2002-011764
• Publication Date: 2002-09-05T17:22:39Z
• Authors: Giovanni Vitale; Maurizio Galderisi; Gelsy Arianna Lupoli; Aldo Celentano; Ilaria Pietropaolo; Nicola Parenti; Oreste de Divitiis; Giovanni Lupoli
• Keywords: Isovolumetric contraction; Isovolumic relaxation time; Tissue Doppler echocardiography; Subclinical infection; Doppler imaging

Pulsed tissue Doppler (TD) is a new ultrasound tool that allows quantification of myocardial regional wall motion. To investigate the cardiac effects subclinical hypothyroidism (SH), present study assessed left ventricular (LV) function in SH by pulsed TD. Twenty women with and 20 healthy underwent standard echocardiograms TD, placing sample volume at level posterior septum LV mitral annulus. Myocardial systolic diastolic velocities time intervals were determined for both levels. Doppler-echocardiographic TD measurements adjusted body surface area heart rate. Standard showed an increases preejection period, period/LV ejection ratio, isovolumic relaxation (IVRT) SH. By analysis, precontraction (PCTm), PCTm/myocardial contraction (RTm) prolonged annulus In whole population, IVRT, PCTm, RTm negatively related to FT4, whereas positively correlated TSH. conclusion, this underscores usefulness detect functional abnormalities due stable SH, mainly changes several segments.