Electrographic seizures in pediatric ICU patients

• DOI: 10.1212/wnl.0b013e31829c5cfe
• Publication Date: 2013-06-22T04:05:24Z
• Authors: Nicholas S. Abend; Daniel H. Arndt; Jessica L. Carpenter; Kevin E. Chapman; Karen M. Cornett; William B. Gallen...; Christopher C. Giza; Joshua L. Goldstein; Cecil D. Hahn; Jason T. Lerner; Tobias Loddenkemper; Joyce H. Matsumoto; Kristin McBain; Kendall B. Nash; Eric Payne; Sarah M. Sánchez; Iván Sánchez Fern...; Justine Shults; Korwyn Williams; Amy Yang; Dennis J. Dlugos
• Keywords: Male; Epilepsy; Adolescent; Incidence; Infant, Newborn; Infant; Electroencephalography; Intensive Care Units, Pediatric; Brain Waves; Statistics, Nonparametric; 3. Good health; Cohort Studies; 03 medical and health sciences; Logistic Models; 0302 clinical medicine; Risk Factors; Child, Preschool; North America; Odds Ratio; Humans; Female; Child; Retrospective Studies

We aimed to determine the incidence of electrographic seizures in children pediatric intensive care unit who underwent EEG monitoring, risk factors for seizures, and whether were associated with increased odds mortality.Eleven sites North America retrospectively reviewed a total 550 consecutive units monitoring. collected data on demographics, diagnoses, clinical mental status at onset, background, interictal epileptiform discharges, length stay, in-hospital mortality.Electrographic occurred 162 subjects (30%), which 61 (38%) had epilepticus. Electrographic exclusively subclinical 59 (36%). A multivariable logistic regression model showed that independent included younger age, prior an abnormal initial diagnosis epilepsy. Subjects epilepticus greater death, even after adjusting background neurologic category.Electrographic are common among unit, particularly those specific factors. occurs more than one-third is higher mortality.