Botulinum A toxin for cranial‐cervical dystonia

• DOI: 10.1212/wnl.37.4.616
• Publication Date: 2012-05-13T12:42:40Z
• Authors: Joseph Jankovic; Janet Orman
• Keywords: Blepharospasm; Cervical dystonia; Spasmodic Torticollis; Focal dystonia; Spasmodic dysphonia

We studied the effects of botulinum A toxin in 12 patients with blepharospasm and 10 oromandibular-cervical dystonia received a double-blind manner. All improved, 71.6% on clinical rating score, 60.7% by self-assessment, 38.9% video-rating; there was no improvement placebo. The beneficial lasted mean 12.5 weeks (range, 5 to 28). Only 37.5% improved. Patients pharyngeal spasmodic dysphonia also