Validation of the Smartphone Brain Scanner for the Detection of Epileptiform Discharges among Epilepsy Outpatients in Bhutan (S52.003)

• DOI: 10.1212/wnl.86.16_supplement.s52.003
• Publication Date: 2023-12-07T09:29:56Z
• Authors: Erica McKenzie; Andrew Lim; Edward Leung; Andrew Cole; Rodrigo Zepeda Ga...; Alice Lam; Ronald Thibert; Esther Bui; Damber Nirola; Sonam Deki; Lhab Tshering; Liesly Lee; Sarah Clark; Joseph Cohen; Jo Mantia; Kate Brizzi; Sarah Wahlster; Tali Sorets; Mikkel Aagaard; Arkadiusz Stopczy...; Lars Hansen; Sydney Cash; Farrah Mateen
• Keywords: Garcia

Objective: To assess the Smartphone Brain Scanner-2 (SBS2)'s ability to detect abnormal and epileptiform cortical discharges compared standard electroencephalogram (EEG) among people with epilepsy (PWE) in Bhutan. Background: The SBS2 is a software application, utilizing 14-lead headset connected wirelessly an Android device. Portable, easily operated, low-cost (<500USD per device), may aid diagnosis of resource-limited settings. Methods: PWE or suspected seizures Bhutan underwent EEG (each ≥20 minutes duration). used circumference-matched EasyCaps ring electrodes positioned at F3, C3, P3, O1, F4, C4, P4, O2, Fz, Cz, Pz, Fpz, A1, A2. (Xltek, Natus) 10-20 system electrode placement peripheral leads. Neurologists, blinded clinical data, categorized recordings as normal abnormal, abnormalities background. Each recording was read once. independently assessed by ≥2 neurologists. A third neurologist group neurologists resolved discrepancies. Results: 215 participants (53[percnt] female, mean age 25 years) completed both no safety tolerability concerns. Epileptiform were present on 25[percnt] 15[percnt] EEGs. For detection all abnormalities, had sensitivity 0.51, specificity 0.84, positive negative predictive values 0.65 0.74 versus EEG. discharges, 0.36, 0.94, 0.68 0.84 Conclusions: specific but not sensitive for have relevance help confirm Sensitivity be improved hardware modifications including addition along temporal chain.