DIFFUSION TENSOR IMAGING OF THE BRACHIAL PLEXUS AND CERVICAL SPINAL NERVE ROOTS: CASE CONTROL STUDY IN CIDP PATIENTS AND CONTROLS (P4.138)

• DOI: 10.1212/wnl.88.16_supplement.p4.138
• Publication Date: 2023-12-07T06:38:40Z
• Authors: Eve Chanson; Matthieu Barriol; Frédéric Taithe; Abderrahim Zerroug; Agnes Lhoste; Bruno Pereira; Louis Boyer; Betty jean; Pierre Clavelou

Objective: The main purpose of this study was to assess the clinical feasibility diffusion tensor imaging (DTI) for diagnosis chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Background: Additionnal criteria such as plexus MRI is rarely used explore CIDP, mainly due lack accessibility and absence consensual protocol exploration plexuses nerve roots. Design/Methods: Between March 2013 December 2015, we prospectively enrolled 15 patients with definite CIDP according EFNS 2010 two control groups: healthy volunteers matched on age sex CMT-1A. Using a 3-T magnetic resonance scanner, obtained DTI scans brachial plexus, prepared Fractional Anisotropy (FA) maps, compared these values between groups. ADC cervical roots diameters STIR sequences were evaluated too. Two neuroradiologists, blinded informations, reviewed studies independently. In performed evaluation electroneuromyography. Results: FA in (median, 0.196 range 0.187; 0.204) significantly lower than those subjects: (median 0.313, 0.288; 0.339) (p Conclusions: Our preliminary data prove reproductibility CIDP. Disclosure: Dr. Chanson has nothing disclose. Barriol Taithe Zerroug Lhoste Pereira Boyer jean Clavelou received personal compensation activities Sanofi Genzyme, Teva, Novartis, Almirall, Biogen.