Origins of the avian neural crest: the role of neural plate-epidermal interactions

• DOI: 10.1242/dev.121.2.525
• Publication Date: 2021-04-26T02:22:42Z
• Authors: Mark A. J. Selleck; Marianne Bronner-...
• Keywords: Neural fold; Neurulation; Epidermis (zoology); Neural cell

ABSTRACT We have investigated the lineage and tissue interactions that result in avian neural crest cell formation from ectoderm. Presumptive plate was grafted adjacent to non-neural ectoderm whole embryo culture examine role of ontogeny crest. Our results show juxtaposition nonneural presumptive induces cells. Quail/chick recombinations demonstrate both prospective epidermis can contribute When similar plate/epidermal confrontations are performed look at derivatives, with either early (stages 4-5) or later 6-10) generation melanocytes sympathoadrenal Interestingly, plates isolated stages form no cells, whereas those give rise but not crest-derived Single analysis determine time which diverges epidermal elucidate timing plate/epidermis during normal development. stage 8 10+ embryos plate/neural segregates around tube closure, suggesting induction is still underway open stages.