Relationship between the Host Cell Endoplasmic Reticulum and the Parasitophorous Vacuole Containing Toxoplasma gondii.

• DOI: 10.1247/csf.22.317
• Publication Date: 2009-10-23T04:38:46Z
• Authors: Edesio J.T. Melo; Wanderley de Souza
• Keywords: Organelle

Tachyzoites of Toxoplasma gondii multiplies within the parasitophorous vacuole (PV) host cell. Simultaneously with parasite division growth takes place. Using immunofluorescence microscopy and antibodies recognizing calreticulin, a nonmuscle functional analogue calsequestrin, 76 kDa glycoprotein localized in endoplasmic reticulum (ER), we showed incorporation ER elements cell into containing-T. gondii. In addition enzyme cytochemistry that glucose-6-phosphatase, an marker ER, is also PV. These observations suggest T. - containing PV at least part due to vacuole.