Comparative Effects Of Two Exercise Modalities On Mots-c Levels In Rats

• DOI: 10.1249/01.mss.0000759832.19743.41
• Publication Date: 2021-07-12T09:03:51Z
• Authors: Yu Fu; Jinghan Yuan; Yanrong Pan; Manda Wang; Ismail Laher; Shunchang Li
• Keywords: Aerobic Exercise; Endurance Training; Treadmill

The mitochondrial-derived peptide MOTS-c is an important cyto-protector in helping maintain mitochondrial function and cellular viability, regulating metabolic homeostasis. It to understand the effects of different exercise modalities on levels various physiological systems order identify its role as a signal physical exercise. PURPOSE: To explore comparative moderate-intensity aerobic resistance serum, skeletal muscle heart. METHODS: Thirty male Sprague-Dawley (SD) rats were randomly divided into three groups: control group (C, n = 10), (A, 10) (R, 10). Rats A ran treadmill at 21 m/min for 60 min per day, 5 days week, while R climbed ladder with incremental loads (50%, 75%, 90% 100% 1RM respectively, 3 times/level, week). training period lasted 4 weeks. Resting muscle, myocardium evaluated by enzyme-linked immunosorbent assays, differences determined using one-way ANOVAs post-hoc tests. RESULTS: Serum significantly higher compared C (both p < 0.01). No difference serum was found between rats. significant effect interaction fiber type modality levels. soleus (p 0.01 0.05, respectively), gastrocnemius 0.05). Myocardial 0.01), no CONCLUSION: Both increased induced uptake muscle. Aerobic may be more effective facilitating slow twitch fibers myocardium. Further research warranted clarify underlying mechanisms. (This study funded National Natural Science Foundation China: Grant Number 31971104)