Effect of Training Load Structure on Purine Metabolism in Middle-Distance Runners

• DOI: 10.1249/mss.0b013e318215d10b
• Publication Date: 2011-03-02T19:30:27Z
• Authors: JACEK ZIELIŃSKI; KRZYSZTOF KUSY; TADEUSZ RYCHLEWSKI
• Keywords: Hypoxanthine; Purine metabolism

There are no studies analyzing the effect of training loads on purine metabolism during long periods.The study's purpose was to evaluate load changes and subsequent detraining in middle-distance runners a 1-yr cycle.In four characteristic points cycle, assigned five intensity zones, pre- postexercise plasma hypoxanthine (Hx) uric acid, erythrocyte Hx-guanine phosphoribosyltransferase (HGPRT) activity were determined 11 male at national level, practicing competitive sport for 8.1 ± 0.3 yr with mean age 22.3 0.7 yr, body mass 73.0 3.4 kg, height 180 2.2 cm.In competition phase (CP), aerobic compensation threshold zones decreased by 65.4% 20.5%, respectively. At same time, anaerobic increased 132.5% VO(2max) zone 74.6% lactic acid tolerance zone. Postexercise Hx significantly CP 6.2 μmol·L(-1). transition (TP) 17.4 Both HGPRT 9.3 nmol·mg(-1)·h(-1). 4.9 , respectively, TP 10.6 12.0 A significant increase 54 revealed merely TP.The is despite very short total duration loads. Elevated preexercise suggests adaptation consisting "permanent readiness" salvage. The leads reverse changes. Probably, concentration may be considered as useful measure status.