Impact of Cardiac Rehabilitation on Renal Function in Patients With and Without Chronic Kidney Disease After Acute Myocardial Infarction

• DOI: 10.1253/circj.cj-13-0779
• Publication Date: 2013-11-11T23:01:17Z
• Authors: Yoichi Takaya; Reon Kumasaka; Tetsuo Arakawa; Takahiro Ohara; Michio Nakanishi; Teruo Noguchi; Masanobu Yanase; Hiroshi Takaki; Yuhei Kawano; Yoichi Goto
• Keywords: Dyslipidemia

Although there is a general fear that exercise training might deteriorate renal function in chronic kidney disease (CKD) patients, the effect of cardiac rehabilitation (CR) on acute myocardial infarction (AMI) patients with CKD remains unknown. We sought to determine whether CR associated amelioration or deterioration such patients.We enrolled 528 AMI who participated 3-month program. Clinical data before and after were compared according participation comorbidities. In without (estimated glomerular filtration rate [eGFR] ≥60ml·min(-1)·1.73m(-2), n=348), peak oxygen uptake (VO2) B-type natriuretic peptide (BNP) improved change eGFR. contrast, (eGFR <60ml·min(-1)·1.73m(-2), n=180), eGFR (48±12 53±15ml·min(-1)·1.73m(-2), P<0.001), together improvements VO2 BNP. When divided into non-active (≤1time/week, n=70) active participants (≥1.1time/week, n=110) attendance CR, showed an improvement (50±10 53±13ml·min(-1)·1.73m(-2), whereas did not participants. Similar results obtained each subgroup hypertension, dyslipidemia, diabetes mellitus. CKD, was VO2, BNP,