Simple Minimal Sedation for Catheter Ablation of Atrial Fibrillation

• DOI: 10.1253/circj.cj-14-1106
• Publication Date: 2014-12-04T00:28:49Z
• Authors: Noboru Ichihara; Shinsuke Miyazaki; Hiroshi Taniguchi; Eisuke Usui; Takamitsu Takagi; Jin Iwasawa; Akio Kuroi; Hiroaki Nakamura; Hitoshi Hachiya; Yoshito Iesaka
• Keywords: Hydroxyzine; Midazolam; Pentazocine; Dexmedetomidine; Nalbuphine; Hydromorphone

Background:Deep sedation or general anesthesia is generally used during atrial fibrillation (AF) ablation. The aim of this study was to report the safety and feasibility minimal AF ablation.Methods Results:One thousand fifty-two ablation procedures in 819 patients (62±11 years, 621 men, 506 paroxysmal) were included. Boluses intravenous hydroxyzine pamoate pentazocine administered, with a maximal dose 100 mg 60 response pain. If pain intolerable requested deeper sedation, moderate using dexmedetomidine propofol introduced. Among consecutive first procedures, procedure completed under 795 (97.1%) without inotropic drugs respiratory support, whereas 20 (2.4%) patients, switched due Patients requiring switch significantly younger than those (53.6±2.3 vs. 62.6±10.4, P<0.01). No abandoned adverse effects sedation. Significant intra-procedural blood pressure decreases not observed any patients. 233 who underwent repeat 6 (2.6%) before procedure. mean time 151±54 min. Cardiac tamponade, unrelated 7 (0.66%) procedures.Conclusions:Minimal might be acceptable vast majority performed electrophysiological laboratories. (Circ J 2015; 79: 346–350)