Prognostic Value of Transthoracic Impedance Cardiography, Amino-Terminal Pro-B-Type Natriuretic Peptide Levels, The Six-Minute Walk Test, and Chest X-Ray in Elderly Patients with Chronic Heart Failure: A Comparative Study in Lithuania

• DOI: 10.12659/msm.945647
• Publication Date: 2024-09-05T15:16:37Z
• Authors: Andrius Ališauskas; Kornelija Dzikevi...; Urtė Rimšaitė; Albinas Naudžiūnas; Haroldas Razvadau...; Diana Zinkienė; Tomas Repečka; Jonas Jucevičius; Saulius Sadauskas
• Keywords: Impedance cardiography

BACKGROUND Chronic heart failure (CHF) is a complex clinical syndrome associated with frequent, recurrent, and long-term hospitalizations. This study from single center in Lithuania aimed to evaluate outcomes 87 elderly patients hospitalized CHF. The methods used included comparing transthoracic impedance cardiography (ICG), amino-terminal pro-B-type natriuretic peptide (NT-proBNP) levels, the six-minute walk test (6MWT), dilatation of right pulmonary artery on chest X-ray (dRPAcXR). MATERIAL AND METHODS sample consisted (49 men 38 women). All subjects underwent 6MWT ICG addition standard CHF tests. median duration follow-up was 23 months. Data about patient were gathered National Medical Record Database. RESULTS By multivariate Cox proportional analysis, thoracic fluid content (TFC) ≥41.1 1/kΩ (hazard ratio [HR] 32.354, 95% confidence interval [CI] 2.758-379.488), NT-proBNP ≥332.0 pmol/L (HR 4.739, CI 1.656-13.559), 6-minute distance (6MWD) ≤203.5 m 3.975, 1.002-15.770), dRPAcXR 5.555, 1.714-18.005) poor prognosis (all P<0.05). correlations between 6MWD other non-invasive diagnostic tests examined this weak moderate. CONCLUSIONS TFC 1/kΩ, pmol/L, m, had combined prognostic value predicting cardiovascular death Therefore, these parameters may be assessment diagnosis cohort.