Case Report: Methimazole-Induced Parotitis - An Unusual Presentation

• DOI: 10.12688/f1000research.149569.2
• Publication Date: 2024-08-27T11:30:05Z
• Authors: Ricky Rana; Emily Krier; Abubakar Tauseef; Jalal Dufani
• Keywords: Thyroid storm; Parotitis

<ns3:p>A 56-year-old female with a medical history of unspecified hyperthyroidism and recent thyroid storm presented to the ED tachycardia, hypertension, bilateral enlarged parotid glands. During previous hospitalization, she was diagnosed started on methimazole. laboratory findings suggested Graves’ disease an acute storm. The patient also complained glands bilaterally. CT tomography neck revealed no calculi but showed extensive fatty replacement, possibly related methimazole use. Treatment propranolol IV hydrocortisone improved function. Due suspicion methimazole-induced parotitis, transitioned reduced dosage for treatment disease, which subsequently her parotitis. Methimazole, standard initial is generally well-tolerated. It can cause adverse reactions; however, parotitis very rare has been documented in only few case reports. Owing limited number reports, its incidence currently unknown. Here, we present as unusual presentation Drug-induced reactions be considered once common causes such viral infection, obstruction, autoimmune diseases are ruled out. involves adjustments supportive care. Methimazole-induced often misdiagnosed overlooked because lack reported cases. This necessitates future research into reaction mechanisms optimal treatment.</ns3:p>