An Initial in Vitro Investigation into the Potential Therapeutic Use of Lucilia Sericata Maggot to Control Superficial Fungal Infections

• DOI: 10.12816/0000271
• Publication Date: 2013-11-19T08:25:31Z
• Authors: Sulaiman M. Alnaimat; Milton Wainwright; Saleem H. Aladaileh
• Keywords: Lucilia; Maggot

In this work an attempt was performed to investigate the in vitro ability of Lucilia sericata maggots control fungi involved superficial fungal infections. A novel GFP-modified yeast culture enable direct visualization ingestion cells by maggot larvae as a method used. The obtained results showed that yeasts were successfully ingested and 1mg/ml excretions/ secretions (ES) considerable anti-fungal activity against growth Trichophyton terrestre mycelium, radial inhibition after 10 days incubation reached 41.2 ±1.8 % relation control, these could lead possible application therapy treatment wounds undergoing infection.