Lung Cancer Attributable to Indoor Radon Exposure in France: Impact of the Risk Models and Uncertainty Analysis

• DOI: 10.1289/ehp.9070
• Publication Date: 2006-05-30T23:00:59Z
• Authors: Olivier Catelinois; Agnès Rogel; Dominique Laurier; Solenne Billon; Denis Hemon; Pierre Verger; Margot Tirmarche
• Keywords: Radon exposure; Attributable risk; Exposure Assessment

The inhalation of radon, a well-established human carcinogen, is the principal-and omnipresent-source radioactivity exposure for general population most countries. Scientists have thus sought to assess lung cancer risk associated with indoor radon. Our aim here this in France, using all available epidemiologic results and performing an uncertainty analysis.We examined exposure-response relations derived from cohorts miners joint analyses residential case-control studies considered interaction between radon tobacco. data come measurement campaigns conducted since beginning 1980s by Institute Radiation Protection Nuclear Safety Directorate-General Health France. We quantified uncertainties coefficients exposures calculated their impact on estimates.The estimated number deaths attributable ranges 543 [90% interval (UI) , 75-1,097] 3,108 (90% UI, 2,996-3,221) depending model considered. This calculation suggests that 2.2% 0.3-4.4) 12.4% 11.9-12.8) these France may be radon.In original work we used different several found regardless relation chosen, appears relatively stable. Smokers can reduce not only reducing concentration but also giving up smoking.