Single uroflow study as a tool in predicting the possibility of abnormal voiding symptoms after the administration of antimuscarinic agents in treating overactive bladder syndrome

• DOI: 10.12891/ceog1799.2015
• Publication Date: 2022-03-15T03:17:53Z
• Authors: H.Y. Chin; K.C. Lin; C. H. Chiang; C. J. Wang
• Keywords: Adult; Tolterodine Tartrate; Urinary Bladder, Overactive; Phenylpropanolamine; Muscarinic Antagonists; Syndrome; Middle Aged; Urination Disorders; Cresols; Urodynamics; Young Adult; 03 medical and health sciences; 0302 clinical medicine; Humans; Female; Benzhydryl Compounds; Aged; Retrospective Studies

The aim of this study was to evaluate the efficacy of uroflowmetry in predicting the possibility of abnormal voiding symptoms following antimuscarinic treatment for overactive bladder syndrome (OAB) in Taiwanese women.A retrospective study was conducted on women with OAB. Forty-five women with abnormal voiding patterns shown by urodynamic study comprised the main group and 38 women with normal voiding patterns comprised the control group. All patients were prescribed two mg tolterodine once daily for one week. Follow-up on complaints of abnormal voiding symptoms was done one week later.One woman in control group and 12 women in main group complained of abnormal voiding symptoms. There was a significant difference in the occurrence of abnormal voiding symptoms after antimuscarinic administration between main study group and control group (26.7 % vs 2.6 %, p = 0.02). CONCLUSIOn: Uroflowmetry is a non-invasive and simple tool to predict the occurrence of abnormal voiding symptoms after antimuscarinic use.