Genomic characterization and distribution of bovine foamy virus in Japan

• DOI: 10.1292/jvms.20-0429
• Publication Date: 2020-09-13T22:05:43Z
• Authors: Mari OKAMOTO; Keisuke OGUMA; Nanako YAMASHITA-...; Toshihiro ICHIJO; Shinichi HATAMA; Maiko ENDO; Maya ISHIKAWA; Takeshi HAGA
• Keywords: 0301 basic medicine; Cattle Diseases; Genomics; Enzootic Bovine Leukosis; 3. Good health; 03 medical and health sciences; Japan; Virology; Leukemia Virus, Bovine; Animals; Spumavirus; Cattle; Female; Phylogeny

Bovine foamy virus (BFV) is distributed through worldwide cattle herds. Although the biological features of BFV are not well understood, appearance clinical manifestation by superinfection with other microorganisms inferred. In Japan, reports genomic characterizations and epidemiology this limited. study, we performed whole sequencing strains Ibaraki No.43, which were isolated in country. Additionally, investigated geographically distant four daily farms to estimate distribution its correlation bovine leukemia (BLV). was throughout Japan; average positive rate 12.7%. The nucleotide sequence identities isolates 99.6% when compared strain USA. phylogenetic tree using env gene showed Ibaraki, No.43 Kagoshima sorted same cluster including USA Chinese strains, while Hokkaido European strains. no clear between BLV could be found, infections likely increase ages. Our data on characteristics will provide important information reveal BFV.