Effect of a DACC dressing on the growth properties and proliferation rate of cultured fibroblasts

• DOI: 10.12968/jowc.2012.21.7.327
• Publication Date: 2014-05-23T16:39:28Z
• Authors: P. Falk; M.L. Ivarsson
• Keywords: Viability assay

• Objective: To study the morphology and proliferation of cultured fibroblasts in combination with an experimental wound-healing model using fibroblasts, without presence a hydrophobic, dialkyl carbamoyl chloride (DACC) dressing (Sorbact; Abigo Medical AB). Method: Human dermal were cell viability investigated. Proliferation was investigated XTT assay. An employed, whereby mechanical damage inflicted to surface fibroblasts. The healing closure wound then monitored DACC dressing. Results: Fibroblasts did not adhere easily material. increased average rate by 50% compared untreated control medium (p < 0.05). significantly more than 100% after 72 hours 0.05) healing, only. Conclusion: enhanced observed different types wounds might be explained increase growth cells area. Declaration interest: This work supported ABIGO AB, Sweden. All expenses for culture materials technical performed at laboratory funded ABIGO. authors have no conflicts interest declare.