The Effects of Anti-thyroid Drugs on Lipoproteins and Insulin Resistance in Graves’ Disease: A Randomized Clinical Trial

• DOI: 10.12997/jla.2024.13.3.358
• Publication Date: 2024-09-25T13:29:41Z
• Authors: Wismandari Wisnu; Idrus Alwi; Nafrialdi Nafrialdi; Tjokorda Gde Dale...; Nico Iswanto Pantoro; Calysta Nadya Wijaya; Dicky Levenus Tah...; Tri Juli Edi Tarigan; Imam Subekti

Graves' disease (GD) is characterized by thyroid overactivity. Anti-thyroid drugs (ATDs), such as propylthiouracil (PTU) and methimazole (MMI), are commonly used for GD treatment, studies have suggested a link between these elevated lipoprotein levels. However, data on their effects lipoproteins, insulin resistance, or low-density receptor (LDL-R) levels lacking, both in Indonesia other countries. This study investigated changes LDL-R, resistance markers with ATD treatment.