An Experimental Study on the Evaluation of Boerhavia Diffusa in the Treatment of Psoriasis in Albino Mice

• DOI: 10.13005/ojc/400224
• Publication Date: 2024-05-01T10:09:13Z
• Authors: Vinay Kumar; Pawan Prajapati; Gauri Goyal; Virendra Pratap S...; Ashutosh Mishra
• Keywords: 0301 basic medicine; 0303 health sciences

Psoriasis, impacting 2-3% of the population, poses a chronic challenge. Conventional treatments having limited effectiveness and adverse effects; recent immunological insights foster targeted therapies, while herbal medications gain attention for safety accessibility. The current research aimed to assess efficacy Boerhavia diffusa in mitigating psoriasis induced by imiquimod mice. Study albino mice using 5% cream 5 days, then treated with (1% 3%) Tazarotene (0.1%). Parameters were assessed study viz. PASI score, spleen weight/body weight ratio, serum inflammatory markers (IL-17, IL-23, TNF-α), skin histopathology. Mice exhibited noteworthy elevations markers, which effectively suppressed applications. Topically application significantly ameliorated psoriasis, suggesting it as promising, well-tolerated alternative enhance quality life affected individuals.