An Experimental Study on the Evaluation of Boerhavia Diffusa in the Treatment of Psoriasis in Albino Mice

0303 health sciences 03 medical and health sciences
DOI: 10.13005/ojc/400224 Publication Date: 2024-05-01T10:09:13Z
ABSTRACT
Psoriasis, impacting 2-3% of the population, poses a chronic challenge. Conventional treatments having limited effectiveness and adverse effects; recent immunological insights foster targeted therapies, while herbal medications gain attention for safety accessibility. The current research aimed to assess efficacy Boerhavia diffusa in mitigating psoriasis induced by imiquimod mice. Study albino mice using 5% cream 5 days, then treated with (1% 3%) Tazarotene (0.1%). Parameters were assessed study viz. PASI score, spleen weight/body weight ratio, serum inflammatory markers (IL-17, IL-23, TNF-α), skin histopathology. Mice exhibited noteworthy elevations markers, which effectively suppressed applications. Topically application significantly ameliorated psoriasis, suggesting it as promising, well-tolerated alternative enhance quality life affected individuals.
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