Tumor apparent diffusion coefficient value and ratio in magnetic resonance imaging on cervical cancer

• DOI: 10.13181/mji.oa.257715
• Publication Date: 2025-05-23T02:36:12Z
• Authors: Trifonia Pingkan ...; Septelia Inawati ...; Sawitri Darmiati; Fitriyadi Kusuma; Sri Mutya Sekarutami; Lisnawati; Joedo Prihartono; Muhammad Ilyas; Ginva Amalia; Khalida Ikhlasiya...
• Keywords: Value (mathematics)

BACKGROUND Diffusion-weighted magnetic resonance imaging (DW-MRI) is a noninvasive, non-contrast sequence for cancer detection. Research involving DW-MRI in cervical has revealed lower apparent diffusion coefficient (ADC) values. This study aimed to evaluate the difference tumor ADC values and ratios (tumor-to-urine tumor-to-muscle) with respect staging (early versus late) histopathology (squamous cell carcinoma adenocarcinoma). METHODS retrospective included 56 patients cancer, divided into early- late-stage groups. was performed all patients, value, ratio between urine (ADC ratiot−u), gluteal muscle ratiot−m) were measured. Statistical methods employed assess ratiot−u, ratiot−m stages histopathological findings. RESULTS The median value early-stage group than (0.75 × 10−3 mm²/s 0.8 mm²/s, p = 0.022). However, no differences observed ratiot−u concerning staging, nor findings (p 0.29, 0.67 0.35, respectively), significant 0.153) 0.260). In receiver operating characteristic analysis, 75.0% sensitive 50.0% specific predicting cut-off of 0.750 mm2/s. CONCLUSIONS significantly suggesting that valuable potential characterizing staging.