Determination of inorganic arsenic in seafood: Emphasizing the need for certified reference materials

• DOI: 10.1351/pac-con-11-10-03
• Publication Date: 2012-01-10T18:21:49Z
• Authors: Ásta Heiðrún Pétu...; Helga Gunnlaugsdó...; Hrönn Jörundsdóttir; Andrea Raab; Eva M. Krupp; Jörg Feldmann
• Keywords: Certified reference materials; Microwave digestion

To evaluate the accuracy and robustness of an extraction method, utilizing -alkaline-ethanolic solution microwave heating, certified reference material (CRM) TORT-2 was subjected to three different instrumental methodologies: high-performance liquid chromatography (HPLC), coupled with without post-column hydride generation; inductively plasma-mass spectrometry (ICP-MS); HPLC-hydride generation-atomic fluorescence (HPLC-HG-AFS). The methods gave a consistent value inorganic arsenic (As) which is near mean reported values in literature, which, however, range by factor 10. Inorganic As, defined here as all As species that do not have As–C bond, is, sum arsenite arsenate any thiol-bound found be less than 4 % total concentration 12 samples fish meal when this method followed HPLC-ICP-MS. date, there no seafood-based compare order validate findings. This illustrates difficulties quantitative determination seafood need for proficiency tests introduce legislation maximum level feed.