Exoscope-based videocapillaroscopy system for in vivo skin microcirculation imaging of various body areas

• DOI: 10.1364/boe.420786
• Publication Date: 2021-06-24T04:00:21Z
• Authors: Alexander S. Mach...; Mikhail V. Volkov; Demid D. Khokhlov; Ekaterina D. Lovc...; Andrey V. Potemkin; Inna V. Danilycheva; Irina V. Dorofeeva; Andrey E. Shulzhenko
• Keywords: 0103 physical sciences; 01 natural sciences

The capillary system immediately responds to many pathologies and environmental conditions. Accurate monitoring of its functioning often enables early detection various diseases related disorders in skin microcirculation. To expand the scope capillaroscopy application, it is reasonable visualize assess blood microcirculation exactly areas inflamed skin. Body vibrations, breathing, non-flat surface other factors hamper application conventional capillaroscopes outside nailfold area. In this paper, we propose an exoscope-based optical for high-quality non-invasive computational imaging network body. image matching tracking temporal intensity variations allow detecting presence pulsations, precise mapping capillaries photoplethysmogram acquisition. We have demonstrated efficiency proposed approach experimentally by