Theoretical model for en face optical coherence tomography imaging and its application to volumetric differential contrast imaging

• DOI: 10.1364/boe.491510
• Publication Date: 2023-05-22T09:00:19Z
• Authors: Kiriko Tomita; Shuichi Makita; Naoki Fukutake; Rion Morishita; Ibrahim Abd El-Sadek; Pradipta Mukherjee; Antonia Lichtenegger; Junya Tamaoki; Lixuan Bian; Makoto Kobayashi; Tomoko Mori; Satoshi Matsusaka; Yoshiaki Yasuno
• Keywords: Sample (material); Speckle noise

A new formulation of the lateral imaging process point-scanning optical coherence tomography (OCT) and a differential contrast method designed by using this are presented. The is based on mathematical sample model called dispersed scatterer (DSM), in which represented as material with spatially slowly varying refractive index randomly distributed scatterers embedded material. It shown that represents meaningful OCT image speckle two independent quantities. complex signal processing images, physical numerical processes jointly formulated same theoretical strategy case OCT. formula shows provides structure. This validated measuring vivo vitro samples.