Miniaturized head-mounted device for whole cortex mesoscale imaging in freely behaving mice

• DOI: 10.1364/brain.2021.bth2b.3
• Publication Date: 2021-11-05T14:33:23Z
• Authors: Mathew L Rynes; Daniel Surinach; Samantha Linn; Michael Laroque; Vijay Rajendran; Judith Dominguez; Orestes Hadjistam...; Zahra S Navabi; Leila Ghanbari; Gregory W Johnson; Mojtaba Nazari; Majid Mohajerani; Suhasa B Kodandar...
• Keywords: Calcium imaging

The mini-mScope is a wide-field miniaturized, head-mounted fluorescence microscope for imaging in freely behaving mice. We demonstrate recording mesoscale calcium activity across the dorsal cortex during sensory-evoked stimuli, open field behaviors, and social interactions.