Virtual histological staining of label-free autopsy tissue sections via deep learning

• DOI: 10.1364/cleo_at.2024.af1b.4
• Publication Date: 2024-09-05T15:25:07Z
• Authors: Yuzhu Li; Nir Pillar; Jingxi Li; Tairan Liu; Di Wu; Songyu Sun; Guangdong Ma; Kevin de Haan; Luzhe Huang; Yijie Zhang; Sepehr Hamidi; Anatoly Urisman; Tal Keidar Haran; William Dean Wallace; Jonathan E. Zucke...; Aydogan Ozcan

We present deep learning-based virtual staining of label-free autopsy tissue sections, eliminating severe autolysis-induced artifacts caused by delayed fixation inherent in traditional histochemical H&E staining.