Theoretical versus empirical measures of retinal magnification for scaling AOSLO images

• DOI: 10.1364/josaa.435917
• Publication Date: 2021-08-12T15:30:10Z
• Authors: H. Heitkotter; A. E. Salmon; R. E. Linderman; J. Porter; J. Carroll
• Keywords: 03 medical and health sciences; 0302 clinical medicine; Ophthalmoscopes; Humans; Retina

The adaptive optics scanning light ophthalmoscope (AOSLO) allows cellular resolution imaging of the living retina. accuracy many quantitative measurements made from these images requires accurate estimates lateral scale images. Here, we used trial lenses, which are known to affect relative magnification retinal image, compare empirical measures image with theoretical a four-surface optical model. model overestimated empirically determined change in 70% subjects examined, albeit varying degrees. While origin for differences between is not known, residual accommodation during likely contributes this variability magnification. These data provide an opportunity derive improved scaling error structural metrics extracted AOSLO